Amyloid β-Peptide (1-42) human
Amyloid β-Peptide (1-42) human
Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
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| CAT# | R1193 |
| Chemical Structure |  |
| CAS | 107761-42-2 |
| Synonyms/Alias | β-Amyloid (1-42), human |
| M.F/Formula | C203H311N55O60S |
| M.W/Mr. | 4514.04 |
| Sequence | One Letter Code: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Three Letter Code: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-GIn-L ys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-lle-lle-Gly-Leu-Met-Val-Gly-Gly-Val-Val-lle-Ala |
| Biological Activity | Human form of the predominant amyloid β-peptide found in the brains of patients with Alzheimer's disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic. |
| Storage | Desiccate at -20°C |
Solubility | Soluble to 1 mg/ml in 50mM Tris buffer |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
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