Luteinizing Hormone-Releasing Hormone (LHRH) and Analogs

Cetrorelix Acetate

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CAT#
10-101-09
Synonyms/Alias
Cetrotide; SB 7; SB-75; Cetrorelix; Cetrorelixum; CHEBI:59224; AIDS085159; AIDS-085159; AIDS 085159; HS-2008; HS2008; HS 2008; D07665
CAS No.
120287-85-6 (net)
Sequence
Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 acetate salt
M.W/Mr.
1431.04
Molecular Formula
C70H92ClN17O14
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Cetrorelix acetate is used to treat hormone-sensitive cancers of the prostate and breast (in pre-/perimenopausal women) and some benign gynaecological disorders.
Description
Cetrorelix acetate (INN, USAN, BAN) (trade name Cetrotide) is an injectable gonadotropin-releasing hormone (GnRH) antagonist. A synthetic decapeptide, works by blocking the action of GnRH upon the pituitary, thus rapidly suppresses the production and action of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Areas of Interest
Hormonal therapy

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