DAMME is a stable synthetic analog of methionine enkephalin. Actions are similar to those of methionine enkephalin. It can be reversed by narcotic antagonists such as naloxone. It is one of the best-known analogs that has undergone fairly extensive clinical testing.
CAT# | 10-101-79 |
CAS | 64854-64-4 (net) |
Synonyms/Alias | D-Ala(2); MePhe(4); Met(0)-ol-enkephalin; FK 33-824; FK-33-824; FK-33824; CID11758339; DL-tyrosyl-DL-alanyl-glycyl-N-methyl-DL-phenylalanyl-S-oxo-DL-methioninol;Tyr Ala Gly MePhe Met OH; Tyr-Ala-Gly-MePhe-Met-OH |
Chemical Name | 2-amino-N-[1-[[2-[[1-[(1-hydroxy-4-methylsulfinylbutan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide |
M.F/Formula | C29H41N5O7S |
M.W/Mr. | 603.73 |
Sequence | One Letter Code: YAGFX Three Letter Code: H-DL-Tyr-DL-Ala-Gly-DL-N(Me)Phe-DL-Met(O)-ol |
Application | DAMME exerts a potent analgesic effect after systemic administration. |
Areas of Interest | Analgesics |
* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
Developed by the German company Hoechst Marion Roussel and derived from genetic modification of hirudin, lepirud ...
An overview of Palmitoyl pentapeptide-4 The potential of topical peptides to improve aging skin has been widely discussed in ...
GR 64349 is a selective and potent NK2 agonist (EC50 = 3.7 nM in rat colon) with activity comparable to that of ...
Background Aclerastide, one angiotensin receptor agonist, is the active ingredient of DSC127 and its general structure is sho ...
Dipeptide diaminobutyroyl benzylamide diacetate, a biologically active polypeptide, classified as a neuropeptide ...