Edotreotide is a chelated octreotide derivative with somatostatin activity. Edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of octreotide and chelated via dodecanetetraacetic acid (DOTA). Like octreotide, this edotreotide binds to somatostatin receptors (SSTRs), especially type 2, present on the cell membrane of many types of neuroendocrine tumors.
CAT# | 10-101-210 |
Chemical Structure | |
CAS | 204318-14-9 |
Synonyms/Alias | DOTA-[TYR3]-OCTREOTIDE;DOTATOC;DOTA-FCYWKTCT-OL (DISULFIDE BRIDGE: 2-7);DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OL (DISULFIDE BRIDGE: 2-7);[DOTA-DPHE1, TYR3]OCTREOTIDE;DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THREONINOL;EDOTREOTIDE;4,7,10-TRICARBOXYMETHYL-1,4,7,10-TETRAAZA-CYCLODODECAN-1-YL-ACETYL-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-L-THREONINOL, (DISULFIDE BOND) |
M.F/Formula | C65H92N14O18S2(netpeptide) |
M.W/Mr. | 1421.66 |
Sequence | Three Letter Code: DOTA-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide |
Biological Activity | Edotreotide is used in the Diagnosis and Staging of Tumors Expressing Somatostatin Receptors. It is an Indicator and Reagent. |
* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
PBP 10 (RhoB-Glu-Arg-Leu-Phe-Glc-Val-Lys-Glc-Arg-Arg) is a 10-aa-long rhodamine-linked and membrane-permeable pe ...
PKC (19-36), a synthetic peptide of the pseudosubstrate domain of the kinase, is a selective inhibitor of prote ...
Huwentoxin IV, a 35-amino-acid-residue polypeptide from Chinese tarantula Ornithoctonus huwena venom, is a kind ...
L-ornithine α-ketoglutarate monohydrate, with some synonyms like OKG, OAKG and L-ornithine 2-oxoglutarate monohy ...
Tandem P-domain weak inward rectifying K+ (TWIK)-related K+ channel 1 (TREK-1) and TWIK-related acid-sensitive K ...