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APIs

Dynorphin A(1-13)

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CAT#
10-101-12
Synonyms/Alias
dynorphin (1-13); dinorphinA (1-13); Dynorphin A; DynorphinA; Dynorphin-A; Dynorphin 1-13; Dynorphin1-13; dynorphin(1-13); 1-13-Dynorphin A; LS-63662; LS63662; LS 63662
CAS No.
72957-38-1 (net)
Sequence
H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys- Leu-Lys-OH acetate salt
M.W/Mr.
1603.99
Molecular Formula
C75H126N24O15
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Dynorphin A appears to reduce morphine requirements in postoperative patients.
Description
Dynorphin A(1-13), a version of dynorphin A containing only the first 13 amino acids of the peptide, in the rat spinal cord has additive effects. When dynorphin A1-13 was injected into the intracerebroventriulcar (ICV) region of the brain, it has an antagonist effect on morphine-induced analgesia.
Areas of Interest
Analgesia
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