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APIs

Endothelin-1 (human, bovine, dog, mouse, porcine, rat) Acetate

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CAT#
10-101-82
Synonyms/Alias
ET-1; Endothelin-1; Endothelin1; Endothelin 1
CAS No.
117399-94-7 (net)
Sequence
H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH acetate salt (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11)
M.W/Mr.
2491.94
Molecular Formula
C109H159N25O32S5
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Endothelin-1 is a highly potent vasoconstrictor which is synthesized in the vascular endothelium and many other tissues.
Description
Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Also ET-1 plays a central role in lung fibrosis.
Areas of Interest
Cardiovascular disease
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