Glucagons and Glucagon-Like Peptides (GLP-1 / GLP-2)

Exendin (9-39) Acetate

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CAT#
10-101-83
Synonyms/Alias
Ex4 peptide; Exendin9-39
CAS No.
133514-43-9 (net)
Sequence
H-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt
M.W/Mr.
3369.8
Molecular Formula
C149H234N40O47S
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Exendin (9-39) is a GLP-1 (glucagon-like peptide-1) receptor antagonist and a competitive inhibitor of exendin-3 and exendin-4.
Description
Exendin (9-39) is a competitive GLP-1 (glucagon-like peptide 1) receptor antagonist. Exendin (9-39) blocks the stimulatory action of GLP-1 amide, exendin-3 and exendin-4 on cAMP production in pancreatic acini. In addition, exendin (9-39) was showed not to interfer the insulin normal secretion.
Areas of Interest
Diabetes
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