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Gonadorelin Acetate

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CAT#
10-101-19
Synonyms/Alias
GnRH; Gonadotropin-releasing hormone; LHRH; Luteinizing hormone-releasing factor acetate (salt) hydrate; Dirigestran; Fertagyl; Gonadoliberin; Hypocrine; Luliberin; Lutrefact; Relefact; Luforan; Lutamin; Lutal
CAS No.
34973-08-5
Sequence
Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 acetate salt
M.W/Mr.
1242.36
Molecular Formula
C55H75N17O13.C2H4O2
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Gonadorelin is also known as LHRH. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Description
Gonadorelin is a trophic peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released from GnRH neurons within the hypothalamus. The peptide belongs to gonadotropin-releasing hormone family. It constitutes the initial step in the hypothalamic–pituitary–gonadal axis.
Areas of Interest
Hormonal therapy
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