Carbocysteine
Carbocisteine is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.
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| CAT# | 10-101-113 |
| CAS | 638-23-3 |
| Synonyms/Alias | (R)-2-Amino-3-carboxymethylsulfanylpropionic acid; 3-[(Carboxymethyl)thio]alanine; AHR-3053; S-(Carboxymethyl)-L-cysteine; LJ-206; Carbocisteine; Carbocistein; Carbocysteine; DF 1794Y; Mucofan; PectDrill; Reomucil; Superthiol sirup; NSC 14156; NSC-14156; NSC14156;S-Carboxymethyl-L-cysteine |
| Chemical Name | (2R)-2-amino-3-(carboxymethylsulfanyl)propanoic acid |
| M.F/Formula | C5H9NO4S |
| M.W/Mr. | 179.19 |
| Sequence | H-Cys(carboxymethyl)-OH |
| Labeling Target | Glutathione S-transferase P |
| Application | Respiratory tract disorders |
| Appearance | Solid powder |
| Purity | >98% (or refer to the Certificate of Analysis) |
| Biological Activity | Carbocysteine is a compound formed when iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expectorant action. |
| Areas of Interest | Cardiovascular System & Diseases
Pituitary & Hypothalamic Hormones |
| Functions | S-nitrosoglutathione binding |
| Disease | Gastrointestinal ulcer;
Gastrointestinal hemorrhage |
| Source# | Synthetic |
Size | 100 g; |
Solubility | Soluble in DMSO |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Short-term Storage Conditions | Dry, dark and at 0 - 4 °C |
Long-term Storage Conditions | -20 °C |
Format | neat |
Organism | Human |
InChI | InChI=1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1 |
InChI Key | GBFLZEXEOZUWRN-VKHMYHEASA-N |
Canonical SMILES | CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)OCC2=CC=CC=C2)C(=O)O |
Isomeric SMILES | C([C@@H](C(=O)O)N)SCC(=O)O |
BoilingPoint | 417.3±45.0 °C at 760 mmHg |
ShelfLife | >2 years if stored properly |
Melting Point | 208-213 °C (dec.) |
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