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Leuprolide Acetate

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CAT#
10-101-22
Synonyms/Alias
Leuprorelin; (Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH; Lupron; leuprolide; Enantone
CAS No.
74381-53-6
Sequence
Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt acetate salt
M.W/Mr.
1269.46
Molecular Formula
C59H84N16O12.C2H4O2
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
As a LH-RH (GnRH) analog, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in In Vitro Fertilization (IVF).
Description
Leuprolide acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Areas of Interest
Hormonal therapy
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