Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.
CAT# | R1513 |
Chemical Structure | |
CAS | 20449-79-0 |
Synonyms/Alias | Honeybee melittin; Bee venom melittin; Forapin |
M.F/Formula | C₁₃₁H₂₂₉N₃₉O₃₁ |
M.W/Mr. | 2846.46 |
Sequence | One Letter Code: GIGAVLKVLTTGLPALISWIKRKRQQ-NH2 three Letter Code: Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2 |
Biological Activity | Inhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor. |
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