Protease-Activated Receptor-2, amide

Protease-Activated Receptor-2, amide (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.

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CAT#R1637
Chemical Structure
CAS190383-13-2
Synonyms/AliasThrombin Receptor-Like 1 (1-6) amide (human), SLIGKVamide, Proteinase Activated Receptor 2 (1-6) amide (human), Coagulation Factor II Receptor-Like 1 (1-6) amide (human)
M.F/FormulaC28H54N8O7
M.W/Mr.619.68
SequenceOne Letter Code: SLIGKV-NH2
three Letter Code: Ser-Leu-Ile-Gly-Lys-Val-NH2
Biological ActivityProtease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2.
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