CAT# | V1314 |
Chemical Structure | |
CAS | 87403-73-4 |
M.F/Formula | C135H214N34O40S |
M.W/Mr. | 2985.46 |
Sequence | One Letter Code: HADGVFTSDFSKLLGQLSAKKYLESLM Three Letter Code: H-His-Ala-Asp-Gly-Val-Phe-Thr-Ser-Asp-Phe-Ser-Lys-Leu-Leu-Gly-Gln-Leu-Ser-Ala-Lys-Lys-Tyr-Leu-Glu-Ser-Leu-Met-NH2 |
Biological Activity | Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets display enhanced glucose-induced insulin secretion. |
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