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This peptide is derived from the HIV-1 Nef binding portion of full-length human Beclin-1 protein (amino acids 267-299). Beclin-1 protein is an autophagy inducing agent that may trigger cellular adaptation, survival, or cell death. When conjugated to the cell-permeable peptide, it can successfully enter cells and induce autophagy.
Soluble in water or DMSO. Avoid repeated freezing and thawing.