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Terlipressin Acetate

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CAT#
10-101-38
Synonyms/Alias
glipressin; glycylpressin; glypressin; Remestyp; terlypressin; TGLVP; triglycylvasopressin; triglycyl lysine vasopressin; Terlipressine; Terlipressinum; Terlipressina; Terlipressina; EINECS 238-680-8; LS-161411
CAS No.
14636-12-5
Sequence
H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 acetate salt (Disulfide bond)
M.W/Mr.
1227.4
Molecular Formula
C52H74N16O15S2
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Terlipressin has been used as a vasoactive drug in the management of low blood pressure. It also indicates to be used in norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.
Description
Terlipressin is a synthetic analog of vasopressin and is used as a vasoactive drug in the management of hypotension. It is a prodrug, which is converted to (Lys8)- vasopressin after removal of the N-terminal triglycine in vivo. Terlipressin has a longer duration of action and a better safety profile than the parent compound.
Areas of Interest
Vasoactive drug
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