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Category Archives: drug discovery

29Apr/19

Sulforaphane, an anticancer substance.

April 29, 2019drug discovery, Newsanti-cancer, Sulforaphaneppt

Sulforaphane, chemical name is 1-isothiocyanate-4-methanesulfonyl butane, also known as “sulforaphane”, which is a common antioxidant and rich in broccoli, cabbage, broccoli, kale, carrots, and other cruciferous plants. Some research showed it isRead More…

15Apr/19

Scientists identify potential target protein aggregates for Alzheimer’s disease.

April 15, 2019drug discovery, NewsAlzheimer’s diseaseppt

Recently, a study published in the international journal Stem Cell Reports, Scientists from institutions such as the University of Paris IV have identified potential targets for the treatment of Alzheimer’s disease. TheRead More…

14Feb/19

Progress of several anti-aging therapies

February 14, 2019drug discoveryaging, cosmeticsppt

For thousands of years, a human has never stopped chasing the dream of “immortality”. With the development of biology, we have a new understanding of the word “immortality” and recognize the boundaries ofRead More…

29Jan/19

Alzheimer’s disease and β-amyloid protein

January 29, 2019drug discoveryAlzheimer’s disease, Aβppt

Alzheimer’s disease (AD) is the most common cause of dementia and is considered the biggest public health hazard of our generation, affecting more than 20 million people. About 135 million people willRead More…

28Sep/18

Alzheimer’s disease and diabetes: hope for inhibitors against amyloid plaques

September 28, 2018drug discoveryppt

Amyloid self-assembly is linked to the pathogenesis of Alzheimer’s disease (AD) and type Ⅱ diabetes (T2D), Several teams of scientists around the world are working on finding ways to prevent amyloid plaque formation inRead More…

31Aug/18

Agonists and antagonists for NPY-family receptors

August 31, 2018drug discoveryppt

Peptide ligands Over the past four years there’s been considerable progress in the development of novel selective analogs of NPY. A number of these analogs have been directed toward discovering tools to understand theRead More…

30May/18

The application of Peptide nucleic acids (PNAs)

May 30, 2018drug discoveryAntibacterial, Antibiotics, Antiviral, Fluorescence In Situ Hybridization, Nanoparticles, Peptide nucleic acids, PNAs, Polymerase Chain Reactionppt

The definition of Peptide nucleic acids (PNAs) PNAs are synthetic DNA analogs in which the phosphodiester backbone is replaced by repetitive units of N-(2-aminoethyl) glycine to which the purine and pyrimidine bases are attached viaRead More…

19Apr/18

Novel neuropeptide may hold clues to the risk of obesity and diabetes

April 19, 2018drug discoverydiabetes, Neuropeptide, Obesity, spexinppt

Obesity is a chronic, multidimensional problem which is being increasingly seen in younger patients. Besides obesity is becoming an epidemic in industrialized countries and is continuing to increase in developing countries worldwide.Read More…

30Mar/18

Peptide Therapies in Diabetes Mellitus

March 30, 2018drug discoveryDiabetes Mellitus, Glucagon-like peptide-1, Peptideppt

Diabetes mellitus is a metabolic syndrome that is defined by raised plasma glucose levels, accompanied by complete or partial deficiency of insulin. Type II diabetes contributes to more than 90 % of the diabeticRead More…

26Jan/18

Structure and function of amyloid

January 26, 2018drug discoveryAlzheimer’s disease, amyloidppt

The term ‘amyloid’ was first used in 1854 by Rudolph Virchow to describe abnormal brain tissue that was stained by iodine, suggesting that it was starch-like. It was later discovered that the amyloid deposits, firstRead More…

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