Cell culture technology has been increasingly important for modern scientific research and many industrialized facilities are able to meet the growing demands of biopharmaceutical industry. While in terms of single-use products, they are widely used in medical applications. Clearly, biotech advances make the production of biological products faster, cleaner and more efficient.
In recent forum, academics and industry representatives have described the current situation of biological products. Ten years ago, some scientists doubted that cell culture facilities may not meet the growing demand of future pharmaceutical industry, which is not true. Actually, the rise of cell expression on disposable bioreactors and yield could increase certain production so as to solve the problem of global shortage on biological products. In addition, some demands for biological products might be counted by the ton, but in most cases, a small amount of products is sufficient to meet the needs of some rare diseases.
In fact, drug development has also suffered setbacks. Recent data shows that there are only 250 could reach the candidate standard in 5000 possible molecules. The development of new drugs has reached to a new stage. However, in order to explore a novel compound, it is necessary to avoid the occurrence of time-consuming, laborious but fruitless difficulties. The problem now facing is to find a suitable patient administration system for patients, which might require the use of tiny needles and subcutaneous injection. Whereas, this may demand further efforts, such as high concentration of protein liquid.
Taking active peptide as the example, such peptide from casein is of biological significance and plays an important role in human health. Besides, the manufacture of novel functional food ingredients has been subject to intensive research. As is seen, more sharing of information has benefited more in-depth exchanges within the industry. For example, tangential flow filtration has caused widespread concern on the development and application of technology, which is expected to show in the form of effective filtration filter.
Certainly, bio-pharmaceutical technology should consider viral safety within the scope. However, current technology seems to be very successful, because contaminated products have been controlled to a certain degree. Continuous improvement and development of bio-pharmaceutical industry will make production of biological products more applicant in life sciences research.