US scientists have developed a nano-transport that can deliver a high dose of anti-cancer drugs to cancer cells in a direct and safe way, which can significantly improve the effect of cancer treatments.<\/p>\n Generally, various cancer cells can generate matrix metalloproteinase that can break down the extracellular matrix components. Such enzyme can promote the spread of cancer cells, leading to death of the body. According to the report from San Diego\u2019s official website, because of the decomposition characteristics of enzyme, the research team has invented a nano-sphere that can release drugs under the presence of matrix metalloproteinase.<\/p>\n The researchers loaded anti-cancer drugs into the nano-sphere and wrapped with a polypeptide such as Alarelin Acetate<\/a><\/strong>. Atoms of some drug molecules could be crucial for the effect of toxic drugs. And adding chemical substances that can connect with above atoms tightly within the nano-sphere can make the drugs maintain an inactive state before they reach the tumor through the circulatory system.<\/p>\n When the wrapped polypeptide-containing nano-spheres arrive the cancerous parts, matrix metalloproteinase can release the drug after the shell exploded polypeptide (Antide<\/a><\/strong>). Meanwhile, the released polypeptide can make drug molecules remain in the vicinity of the tumor.<\/p>\n
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