Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney.
CAT# | R1200 |
CAS | 52580-29-7 |
M.F/Formula | C₂₄H₃₇N₇O₈ |
M.W/Mr. | 551.59 |
Sequence | One Letter Code: DRVY 姃three Letter Code: Asp-Arg-Val-Tyr |
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