cyclo[-Arg-Gly-Asp-D-Phe-Lys-]
CAT# | R04029 |
Chemical Structure | |
CAS | 161552-03-0 |
Synonyms/Alias | c(RGDfK) |
M.F/Formula | C27H42N9O7 |
M.W/Mr. | 603.68 |
Sequence | One Letter Code:Cyclo(-RGDfK) Three Letter Code: Cyclo(Arg-Gly-Asp-Phe-Lys) |
Biological Activity | Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface. |
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