Margatoxin

A potent and specific KV1.3 channel blocker, and exhibits no effect at calcium-activated channels. Margatoxin can reduces VEGF-induced transmembrane calcium influxes and nitric oxide production in human endothelial cells.

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CAT#R0995
CAS145808-47-5
Synonyms/AliasMgTX
M.F/FormulaC178H286N52O50S7
M.W/Mr.4178.96
SequenceTIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH
(Disulfide bridge between Cys7 and Cys29, Cys13 and Cys34, Cys17 and Cys36)
Labeling TargetKV1.3 channel
AppearanceWhite lyophilised solid
Purity>98%
ActivityBlocker
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