Penetratin, the first 16 amino acids of which are derived from the third helix of the Antennapedia protein homeodomain, is known as a protein transduction domain (PTD). Penetratin linked to a phosphodiester oligonucleotide is capable of permeating through neuronal cell membranes and down-regulating genes. It contains a nuclear localization sequence and facilitates internalization of cargo into living cells.
CAT# | GR1701 |
M.W/Mr. | 2360.9 |
Sequence | H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gly-Gly-OH |
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