Carperitide

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. ANP (1-28) inhibits endothelin-1 secretion in a dose-dependent way.

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CAT No: HB00119

CAS No: 89213-87-6

Synonyms/Alias: Carperitide;89213-87-6;Cardionatrin;Atriopeptin;alpha-Atriopeptin;Atrial Natriuretic Peptide;Atriopeptins;Auriculin (peptide);Atrial natriuretic peptide A;SUN-4936;Atrial natriuretic peptides;Natriuretic peptides, atrial;Atrial natriuretic factor (99-126);Atrial natriuretic peptide-28 (human reduced);ATRIAL NATRIURETIC FACTOR;85637-73-6;SUN 4936;alpha-Human atriopeptin;Atriopeptin-28 (human);alpha-Atriopeptin (human);Human atriopeptin(1-28);Human atriopeptin(99-126);CCRIS 4930;Atrial Natriuretic Peptide human;Triopeptin (human alpha-component);Carperitide [USAN:INN];UNII-GZ8FA500J0;Cardionatrine;Carperitida;NPPA protein, human;Anp 1-28,human;Atrial natruiretic factor;Natriuretic Peptide, Atrial;Peptides, Atrial Natriuretic;SCHEMBL218549;beta-Atrial Natriuretic Peptide;GZ8FA500J0;alpha-Atrial Natriuretic Peptide;Atrial Natriuretic Factor (1-28) (human) acetate salt;atrial natriuretic factor (ANF);CHEMBL2104386;gamma-Atrial Natriuretic Peptide;CHEBI:135914;NSQLIUXCMFBZME-MPVJKSABSA-N;DTXSID201346607;DTXSID801026506;Atrial Natriuretic Factor Precursors;BDBM50230986;Atrial natriuretic peptide carperitide;AKOS024456845;AT42445;ATRIAL NATRIURETIC PEPTIDE [MI];Atriopeptin-33(rat), 1-de-L-leucine-2-de-L-alanine-3-deglycine-4-de-L-proline-5-de-L-arginine-17-L-methionine-;DA-50791;FA108602;FA110232;L-Seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine cyclic(7->23)-disulfide;L-Seryl-L-leucyl-L-arginyl-L-arginyl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanylglycylglycyl-L-arginyl-L-methionyl-L-aspartyl-L-arginyl-L-isoleucylglycyl-L-alanyl-L-glutaminyl-L-serylglycyl-L-leucylglycyl-L-cysteinyl-L-asparaginyl-L-seryl-L-phenylalanyl-L-arginyl-L-tyrosine cyclic(7-23)-disulfide;ATRIAL NATRIURETIC PEPTIDE [WHO-DD];NS00123867;1366000-58-9;Atrial natriuretic factor (1-28) (human) acetate;Atrial natriuretic factor (1-28) trifluoroacetate;1621001-83-9;Carperitide trifluoroacetate;H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala- Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser- Phe-Arg-Tyr-OH trifluoroacetate (Disulfide bond);H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH acetate;

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M.F/FormulaC127H203N45O39S3
M.W/Mr.3080.5
SequenceOne Letter Code:SLRRSSCFGGRMDRIGAQSGLGCNSFRY
Three Letter Code:H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH
Purity0.98
Biological ActivityCarperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) is a 28-amino acid hormone, that is normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. Carperitide (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine) inhibits endothelin-1 secretion in a dose-dependent way.
TargetEndothelin Receptor
Source#Synthetic
InChIInChI=1S/C127H203N45O39S3/c1-9-64(6)99-121(209)150-52-94(182)151-65(7)100(188)155-76(34-35-91(129)179)109(197)167-85(56-174)104(192)149-53-96(184)153-78(43-62(2)3)102(190)148-54-97(185)154-89(119(207)164-82(48-92(130)180)114(202)169-86(57-175)116(204)163-81(46-67-23-14-11-15-24-67)113(201)158-73(27-18-39-143-125(135)136)107(195)166-84(122(210)211)47-68-30-32-69(178)33-31-68)60-213-214-61-90(171-118(206)88(59-177)170-117(205)87(58-176)168-108(196)74(28-19-40-144-126(137)138)156-106(194)72(26-17-38-142-124(133)134)157-112(200)79(44-63(4)5)161-101(189)70(128)55-173)120(208)162-80(45-66-21-12-10-13-22-66)103(191)147-50-93(181)146-51-95(183)152-71(25-16-37-141-123(131)132)105(193)160-77(36-42-212-8)110(198)165-83(49-98(186)187)115(203)159-75(111(199)172-99)29-20-41-145-127(139)140/h10-15,21-24,30-33,62-65,70-90,99,173-178H,9,16-20,25-29,34-61,128H2,1-8H3,(H2,129,179)(H2,130,180)(H,146,181)(H,147,191)(H,148,190)(H,149,192)(H,150,209)(H,151,182)(H,152,183)(H,153,184)(H,154,185)(H,155,188)(H,156,194)(H,157,200)(H,158,201)(H,159,203)(H,160,193)(H,161,189)(H,162,208)(H,163,204)(H,164,207)(H,165,198)(H,166,195)(H,167,197)(H,168,196)(H,169,202)(H,170,205)(H,171,206)(H,172,199)(H,186,187)(H,210,211)(H4,131,132,141)(H4,133,134,142)(H4,135,136,143)(H4,137,138,144)(H4,139,140,145)/t64-,65-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,99-/m0/s1
InChI KeyNSQLIUXCMFBZME-MPVJKSABSA-N
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