At Creative Peptides, we specialize in providing high-quality, custom peptide synthesis services tailored to your research, pharmaceutical, and industrial needs. Whether you're exploring new drug targets or developing next-generation biomaterials, we deliver reliable, scalable peptide solutions - with precision, speed, and cost-efficiency.
Our custom peptide synthesis services range from research grade to many API peptides. Creative Peptides is proficient in different synthesis methods to meet different needs.
We can synthesize peptides of 200 amino acids and above. Longer peptides can be prepared by recombinant peptide technology.
Lipopeptides Synthesis Service
We offer custom lipopeptide synthesis for vaccine adjuvants, antimicrobial peptide research, and delivery system applications. Our services support lipidation at N-terminal or side chains with flexible chain lengths and formats.
We produce recombinant peptides via E. coli or yeast expression systems, suitable for complex, post-translationally modified peptides. Our services include gene synthesis, expression optimization, and protein purification.
Our custom peptoid synthesis service provides sequence-defined N-substituted glycine oligomers, ideal for protease-resistant biomaterials, therapeutic leads, and bioactive surface coatings.
We specialize in glycopeptide synthesis, incorporating natural or custom-designed carbohydrate moieties to mimic glycosylation patterns. Applications include vaccine development, immune profiling, and structural biology.
We provide reliable oligopeptide synthesis (2-20 amino acids) with high purity and optional labeling or modifications. Suitable for basic research, assay development, and diagnostic applications.
We specialize in custom cyclic peptide synthesis, offering high-quality, stable, and bioactive peptides with enhanced affinity, stability, and protease resistance. Ideal for drug discovery, protein-protein interaction studies, and targeted therapy, our expertise ensures efficient ring closure and scalable production, including disulfide or lactam bridge formations.
Our bicyclic peptide synthesis enables development of ultra-stable peptide scaffolds with enhanced binding affinity and protease resistance. Ideal for therapeutic targeting and molecular probes.
Custom MHC-Peptide Tetramer Synthesis
We provide high-affinity MHC-peptide tetramer synthesis for accurate T-cell epitope identification and immune monitoring. Our custom solutions ensure high purity and precise MHC class I or II loading to match your immunology research needs.
Peptide Nucleic Acid (PNA) Synthesis
Our custom PNA synthesis service offers synthetic DNA analogs with superior hybridization stability and resistance to enzymatic degradation, ideal for antisense therapies, diagnostics, and molecular probes.
We specialize in the synthesis of stapled peptides with hydrocarbon bridges to enhance α-helicity, protease resistance, and cellular uptake-ideal for targeting intracellular protein-protein interactions.
Our advanced synthesis platforms support long peptide production (up to 100+ amino acids) with high yield and purity. We excel in difficult sequences and post-synthesis modifications, including segment ligation and C-terminal amidation.
From milligrams to grams, our large-scale peptide synthesis services ensure consistent quality, batch reproducibility, and regulatory documentation-ideal for preclinical development and commercial applications.
Special Antigen Peptides Services
We design and produce custom antigenic peptides tailored for antibody generation, epitope validation, and vaccine projects. Special formats like phosphorylated, glycosylated, or neoantigen peptides are fully supported.
Peptide Library / Array Synthesis
We offer high-throughput peptide library and array synthesis, enabling systematic screening of epitope specificity, binding affinity, and structure-activity relationships. Ideal for drug discovery, vaccine development, and biomarker research.
Custom Locked Nucleic Acid (LNA) Synthesis
We provide precise LNA synthesis for nucleic acid therapeutics and diagnostics. LNAs offer unmatched hybridization affinity and nuclease resistance, with scalable, customizable production and strict quality control.
Custom Bridged Nucleic Acid (BNA) Synthesis
Our BNA synthesis service delivers modified oligonucleotides with locked conformations, ensuring high thermal stability and affinity for diagnostics and gene regulation studies.
Multiple Antigenic Peptides (MAPs) and Dendrimers
We synthesize MAPs and dendrimeric peptide structures to boost immunogenicity without carrier proteins. Custom branching, linker design, and multivalency options available.
D-Amino Acid Peptide Synthesis
Our team synthesizes D-amino acid-containing peptides to enhance protease resistance and bioavailability. Custom mirror-image peptides are available for stability testing, therapeutic development, or structural studies.
We offer click chemistry-compatible peptides with azide or alkyne groups for rapid, site-specific conjugation. Suitable for bioconjugation, surface immobilization, and probe development.
Custom Peptide Inhibitor Synthesis
We design and synthesize custom peptide inhibitors targeting enzymes, receptors, or protein-protein interactions. Our chemists optimize stability, specificity, and cell permeability to support preclinical research and screening.
After peptide synthesis, each peptide is routinely analyzed by LC-MS, MALDI-MS, or HPLC to confirm the identity and quality of the customized peptide.
All peptides are analyzed by MALDI-MS to determine the molecular weight of the synthesized peptides.
MALDI is an excellent method to determine the presence of the desired product, but it is not sufficient to determine purity. So, all non-crude peptides must be analyzed by reverse-phase HPLC (RP-HPLC) to determine purity. Other QC analysis, such as amino acid analysis, NMR, CE, and peptide content determination can be performed to confirm the quality of customized peptides.
Chromatography (HPLC, TLC, GC, IC)
Chromatography combined with mass spectrometry (LC-MS / ESI)
Spectroscopy (UV-Vis, IR, NMR)
Metal analysis (AAS, ICP, ICP-MS)
Elemental analysis
Titration (acid-base titration, Karl Fischer titration)
Amino acid analysis
Peptide sequencing
Expertise
With years of experience in peptide synthesis and modification, we deliver top-tier peptides.
Precision
We ensure accurate sequence design and synthesis that meets your exact specifications.
Flexibility
Whether you're synthesizing small peptides or large proteins, our services are fully scalable.
Quality control
All peptides are analyzed by MS and HPLC
Unlimited
Short or long peptides, chemical or recombinant peptide technology
Competitive Pricing
High-quality peptides at affordable rates with no compromise on quality.
Confidentiality
We prioritize client confidentiality and secure handling of intellectual property.
Diversity
Large number of conjugations, modifications, and labeling
Peptide Design Consultation
Quotation & Order Confirmation
Solid-Phase Peptide Synthesis (SPPS)
Purification & QC Analysis
Packaging & Worldwide Shipping
Creative Peptides also has extensive experience in the design and production of modified peptides. We provide a variety of peptide modifications, labeling, and bioconjugation with other biomolecules, including
In addition, we also provide a variety of optional peptide analysis, including
Creative Peptides provides one-stop peptide solutions, from peptide synthesis, modification, labeling and conjugation to a wide range of biopolymers and surface attachments. Our peptides conjugation services include, but are not limited to