Aclerastide

Aclerastide is an angiotensin receptor agonist. It can reduce fibrosis and scarring in the healing wounds. This action is more pronounced with longer administration of the peptide after injury. The action of this peptide is blocked by the AT receptor antagonist d-Ala7-angiotensin(1-7), which suggests that this receptor is involved in the healing responses to exogenous NorLeu3-A(1-7). Aclerastide has the potential in accelerating wound repair and reducing scar formation.

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CAT#	10-101-183
CAS	227803-63-6
Synonyms/Alias	Norleu3-a(1-7); UNII-YYD6UT8T47; Asp-arg-nle-tyr-ile-his-pro; DSC127; DSC-127; USB-001;
M.F/Formula	C42-H64-N12-O11
M.W/Mr.	913.0406
Sequence	H-Asp-Arg-Nle-Tyr-Ile-His-Pro-OH
Labeling Target	Angiotensin receptor
Application	Aclerastide is studied for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Activity	Agonist
Biological Activity	Aclerastide, also known as DSC-127; NorLeu-3-A(1-7); NorLeu-3A(1-7), is an angiotensin receptor agonist potentially for the treatment of tissue regeneration in diabetic ulcers.
Disease	Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabeti
Target	Angiotensin Receptor

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-158	Albiglutide	72970.4029	C3232H5032N864O979S41	Inquiry
10-101-18	Glucagon	3482.8	C153H225N43O49S	Inquiry
10-101-59	Liraglutide	3751.2	C172H265N43O51	Inquiry

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-20	Goserelin Acetate	1269.43	C59H84N18O14	Inquiry
10-101-59	Liraglutide	3751.2	C172H265N43O51	Inquiry
R1574	Octreotide	1019.24	C₄₉H₆₆N₁₀O₁₀S₂	Inquiry
10-101-139	Myrcludex B			Inquiry
10-101-285	Teduglutide	3752.08	C164H252N44O55S	Inquiry
R1847	Sermaglutide	4114	C187H291N45O59	Inquiry
R1961	Carbetocin	988.2	C45H69N11O12S	Inquiry

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Source#	Synthetic
Storage	-20°C
Solubility	Soluble in DMSO
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Long-term Storage Conditions	-20 °C
ShelfLife	>2 years if stored properly