L-Aspartyl-L-phenylalanine is a dipeptide inhibitor of angiotensin-converting enzyme (ACE) and a metabolite of the synthetic non-caloric sweetener aspartame. It is formed from aspartame by intestinal intracellular esterases. L-Aspartyl-L-phenylalanine inhibits ACE with a Ki value of 11 µM for the rabbit enzyme. Serum levels of L-aspartyl-L-phenylalanine are positively associated with pancreatic ductal adenocarcinoma.
CAT# | 10-101-305 |
CAS | 13433-09-5 |
Chemical Name | (3S)-3-amino-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid |
M.F/Formula | C13H16N2O5 |
M.W/Mr. | 280.28 |
Sequence | One Letter Code: DF Three Letter Code: L-Asp-L-phe |
Purity | >98 % |
Activity | Inhibitor |
Target | Angiotensin-converting Enzyme (ACE) |
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