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Antigens from Infectious Diseases

BKV (large T antigen)

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CAT#
PPO-H004
Size
1 vial containing 15 nmol ( 25μg) per peptide
Purity
>70% (HPLC-MS)
Format
Freeze dried in amber type glass vial
Application
T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Topics
Infection, AIDS, Cancer chemotherapy, Transplantation, Merkel cell carcinoma, PML and BK nephropathy
Number of peptides
170
Organism
BK polyomavirus
Specifications
Peptide scan (15mers with 11 aa overlap)
Protein Length
691
Protein Name
Large T antigen
Swiss-Prot ID
P14999
References
1."PepMixTM Peptide Pools for Clinical Applications: T cell therapy for viral infections after hematopoietic stem cell transplant"
Leen et al, Application Note (2012)
2."Differential Patterns of Large Tumor Antigen-Specific Immune Responsiveness in Patients with BK Polyomavirus-Positive Prostate Cancer or Benign Prostatic Hyperplasia". Sais et al., J. Virol. (2012)
3."Polyomavirus BK Large T-antigen Derived Peptide Elicits a HLA-DR Promiscuous and Polyfunctional CD4+ T-cell Response". Clin. Vaccine Immunol. (2011)
4."Nucleofection of DCs to Generate Multivirusspecific T Cells for Prevention or Treatment of Viral Infections in the Immunocompromised Host". Gerdemann et al., Molecular Therapy (2009)
5."Prospective Monitoring of Polyomavirus BK Replication and Impact of Pre-Emptive Intervention in Pediatric Kidney Recipients". Ginevri et al., American Journal of Transplantation (2007)
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