Caspofungin

Caspofungin is an antifungal drug, the first of a new class termed the echinocandins from Merck & Co., Inc. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall. Caspofungin is administered intravenously.

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CAT#Z10-101-157
CAS162808-62-0
M.F/FormulaC52H88N10O15
M.W/Mr.1093.31
Labeling TargetBeta-(1,3)-glucan synthase
ApplicationCaspofungin is an antifungal drug, and used for the treatment of esophageal candidiasis and invasive aspergillosis in patients who are refractory to or intolerant of other therapies.
ActivityInhibitor
Biological ActivityCaspofungin (MK-0991; L-743,872) belongs to the echinocandin family, a new class of antifungal agents that act on the fungal cell wall by inhibiting glucan synthesis.
Areas of InterestInfection
Functions1,3-beta-d-glucan synthase activity
DiseaseCandidiasis of the esophagus;
Candidemia;
Intra-Abdominal Candida Abscess;
Candida Pleural Space Infection
TargetAntimicrobial
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