Cholecystokinin Octapeptide (desulfated)
Cholecystokinin Octapeptide (desulfated)
Cholecystokinin (CCK) octapeptide is a peptide hormone found in the intestine and brain, which stimulates digestion, mediates satiety, and participates in anxiety disorders. It is a cleavage product of intact CCK prohormones. The activity of CCK octapeptide (unsulfated) is 1/300 of that of sulfated CCK octapeptide.
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| CAT# | 10-101-247 |
| CAS | 25679-24-7 |
| Synonyms/Alias | CCK-8 (desulfated); Cholecystokinin (CCK) (26-33); 2-desulfo-cholecystokinin-8 (swine) |
| Chemical Name | (3R,6S,9S,15R,18R,21R)-9-((1H-indol-3-yl)methyl)-21-amino-3-((R)-2-hydrazinyl-3-phenylpropanamido)-18-(4-hydroxybenzyl)-6,15-bis(2-(methylthio)ethyl)-4,7,10,13,16,19,20-heptaoxo-5,8,11,14,17-pentaazatricosane-1,23-dioic acid |
| M.F/Formula | C49H62N10O13S2 |
| M.W/Mr. | 1063.23 |
| Sequence | One Letter Code: DYMGWMDP
Three Letter Code: Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2 |
| Application | Peptide hormone |
| Appearance | White or off-white lyophilized powder |
| Purity | 98% |
| Activity | Non-sulfated form of the C-terminal octapeptide of CCK |
| Storage | Desiccate at -20°C |
Solubility | Soluble to 1 mg/ml in 10% acetonitrile / water |
Shipping Condition | +20°C (International: -20°C) |
InChI Key | ZBTPHEHKAHBSMT-YRVFCXMDSA-N |
Canonical SMILES | O=C([C@H](CCSC)NC([C@@H](CC(O)=O)NC([C@@H](CC1=CC=CC=C1)NN)=O)=O)N[C@H](C(NCC(N[C@@H](C(N[C@@H](C(C([C@@H](CC(O)=O)N)=O)=O)CC(C=C2)=CC=C2O)=O)CCSC)=O)=O)CC3=CNC4=CC=CC=C34 |
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