An effective and selective competitive antagonist for α3β2 subunit-containing nicotinic receptors (IC50 = 0.5 - 3.5 nM at α3β2 expressed in Xenopus oocytes), and also potently blocks β3-containing neuronal nicotinic receptors.
CAT# | R0920 |
CAS | 175735-93-0 |
M.F/Formula | C67H103N23O22S4 |
M.W/Mr. | 1710.99 |
Sequence | GCCSNPVCHLEHSNLC-NH2(Disulfide bridge between Cys2 and Cys8, Cys3 and Cys16) |
Labeling Target | α3β2 subunit-containing nicotinic receptor |
Activity | Antagonist |
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