GR 231118 is a potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1, receptors respectively), and also a NPY Y4 receptor agonist (pEC50 values are 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors respectively).
CAT# | R0829 |
CAS | 158859-98-4 |
M.F/Formula | C110H170N34O24 |
M.W/Mr. | 2352.77 |
Sequence | IEPXYRLRY IEPXYRLRY*(Modifications: X = Dpr, Amide Bridge = 2 - 4*, 4 - 2*, Tyr-9 = C-terminal amide) |
Labeling Target | Neuropeptide Y (NPY) Y1 receptor |
Application | A potent NPY1-R antagonist and NPY4-R agonist |
Appearance | White lyophilised solid |
Purity | >99 % |
Activity | Antagonist |
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