Lyn peptide inhibitor is cell-permeable inhibitor of lyn-dependent effects of the il-5 receptor, which blocks binding of lyn tyrosine kinase to βc subunit of il-3/gm-csf/il-5 receptors, blocking lyn activation. It inhibits il-5 receptor-mediated eosinophil differentiation and survival in vitro.
CAT# | R0841 |
CAS | 222018-18-0 |
M.F/Formula | C115H184N30O24 |
M.W/Mr. | 2370.91 |
Sequence | YGYRLRRKWEEKIPNP(Modifications: Tyr-1 = Octadecanoyl-Tyr, Pro-16 = C-terminal amide) |
Labeling Target | IL-5 receptor |
Appearance | White lyophilised solid |
Purity | >98 % |
Activity | Inhibitor |
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