α-Melanocyte-Stimulating Hormone (MSH), amide
α-Melanocyte-Stimulating Hormone (MSH), amide
α-Melanocyte-Stimulating Hormone (MSH), amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.
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| CAT# | R1763 |
| Chemical Structure |  |
| CAS | 581-05-5 |
| Synonyms/Alias | α-Melanocyte-Stimulating Hormone (MSH), amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase. |
| M.F/Formula | C77H109N21O19S |
| M.W/Mr. | 1664.88 |
| Sequence | One Letter Code: Ac-SYSMEHFRWGKPV-NH2
three Letter Code: Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 |
| Biological Activity | Endogenous melanocortin receptor agonist (Ki values are 0.12, 31, 660 and 5700 nM for MC1, MC3, MC4 and MC5 receptors respectively). Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-α, IL-6 and NO and induces anti-inflammatory cytokine IL-10. Inhibits food intake and induces penile erections following i.c.v. administration. |
| Storage | Desiccate at -20°C |
Shipping Condition | Room temperature in continental US; may vary elsewhere. |
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