An antagonist of 14.3.3 proteins (KD ≈80 nM) that induces apoptosis. Competitively inhibits 14-3-3-ligand interactions without requiring phosphorylation, thereby blocks the ability of 14-3-3 binding to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.
CAT# | R1015 |
CAS | 211364-78-2 |
M.F/Formula | C101H157N27O29S3 |
M.W/Mr. | 2309.69 |
Sequence | PHCVPRDLSWLDLEANMCLP |
Labeling Target | 14.3.3 Proteins |
Appearance | White lyophilised solid |
Purity | >98% |
Activity | Antagonist |
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