SN50
SN50, also named NF-KB inhibitor, is a synthetic peptide corresponding to the nuclear localization sequence of NF-KB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-KB signaling, including LPS and TNF-Alpha.
Online Inquiry
| CAT# | R1845 |
| CAS | 213546-53-3 |
| Synonyms/Alias | Nuclear Factor NF-KB Inhibitor SN50; NFkappaB Inhibitor |
| M.F/Formula | C129H230N36O29S |
| M.W/Mr. | 2781.5 |
| Sequence | One Letter Code: AAVALLPAVLALLAPVQRKRQKLMP
Three Letter Code: Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro |
| Application | This peptide is commonly used to evaluate the role of NF-KB signaling in cellular responses. |
| Appearance | Lyophilized solid |
| Purity | ≥97% by HPLC |
| Storage | Store at -20°C for up to 2 years. |
Shipping Condition | Gel Pack |
InChI Key | FAWLNURBQMTKEB-URDPEVQOSA-N |
Canonical SMILES | CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N2CCCC2C(=O)O)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C3CCCN3C(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(C)N |
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
