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Euler-Gaddum Substance P; Hypothalamic Substance P; SP(1-11); SP1-11; SP 1-11; SP
H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 acetate salt
Long-term Storage Conditions
Substance P is a modulator of pain transmission. As an extremely potent vasodilator, it produces significant bronchodilation in normal and asthmatic subjects and a maximal increase in forearm blood flow.
The undecapeptide substance P has a number of peripheral actions which include contraction of smooth muscle, reduction of blood pressure and stimulation of secretory tissues. Substance P also occurs in neurones in the central nervous system. It is of particular interest as a possible neurotransmitter or neuromodulator, released by primary sensory neurones.
Areas of Interest