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APIs

Substance P Acetate

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CAT#
10-101-52
Synonyms/Alias
Euler-Gaddum Substance P; Hypothalamic Substance P; SP(1-11); SP1-11; SP 1-11; SP
CAS No.
33507-63-0 (net)
Sequence
H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 acetate salt
M.W/Mr.
1347.63
Molecular Formula
C63H98N18O13S
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Substance P is a modulator of pain transmission. As an extremely potent vasodilator, it produces significant bronchodilation in normal and asthmatic subjects and a maximal increase in forearm blood flow.
Description
The undecapeptide substance P has a number of peripheral actions which include contraction of smooth muscle, reduction of blood pressure and stimulation of secretory tissues. Substance P also occurs in neurones in the central nervous system. It is of particular interest as a possible neurotransmitter or neuromodulator, released by primary sensory neurones.
Areas of Interest
Diseases diagnosis
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