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Somatostatin & Analogs

Vapreotide Acetate

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CAT#
10-101-44
Synonyms/Alias
RC-160; Octastatin; RC 160; RC160; Vapreotida; DB04894
CAS No.
103222-11-3 (net), 116430-60-5 (acetate) 849479-74-9(ChemIDplus)
Sequence
D-Phe-Cys-Trp-D-Trp-Lys-Val-Cys-Trp-CONH2(disulfide Cys2-Cys7)
M.W/Mr.
1191.44
Molecular Formula
C59H74N12O11S2
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Vapreotide is a synthetic octapeptide somatostatin analog with a different receptor affinity to octreotide. It is used for the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
Description
Vapreotide is a somatostatin analog with a higher metabolic stability than the parent hormone. Vapreotide reduces splanchnic blood flow, inhibits growth hormone release, and inhibits the release of peptides and vasoactive compounds from neuroendocrine tumors.
Areas of Interest
Diseases diagnosis

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