Z-RLRGG-AMC is a fluorogenic substrate for the deubiquitinating enzyme isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases (UCHs) based on the C-termini of ubiquitin with a kcat/Km value of 95 M⁻¹s⁻¹. Together with our product I-1685 it is used in continuous assays for precise mechanistic studies or microtiter plate assays for high-throughput inhibitor screening.
CAT# | R1912 |
Chemical Structure | |
CAS | 167698-69-3 |
Synonyms/Alias | Z-RLRGG-AMC |
Chemical Name | benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[2-[[2-[(4-methyl-2-oxochromen-7-yl)amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate |
M.F/Formula | C40H56N12O9 |
M.W/Mr. | 848.96 |
Sequence | One Letter Code: RLRGG Three Letter Code: Cbz-Arg-Leu-Arg-Gly-Gly-AMC |
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