Z-IETD-FMK is a selective and cell permeable caspase 8 inhibitor. It also inhibits caspase-10. The bis-methyl ester of Z-IETD-FMK blocked CD95-induced apoptosis.
CAT# | HB00018 |
CAS | 210344-98-2 |
Synonyms/Alias | IETD (Modifications: N-terminal benzyloxycarbonyl; C-terminal FMK; Glu-2 = Glu(OMe); Asp-4 = Asp(OMe)) |
M.F/Formula | C30H43FN4O11 |
M.W/Mr. | 654.6894 |
Sequence | Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F |
Labeling Target | Caspase 8 |
Purity | 95/98% |
Activity | Inhibitor |
Areas of Interest | Cancer |
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