Protein kinase Mξ (PKMξ), as an active form of protein kinase C (PKC) isozyme, is necessary and potent for long-term potentiation (LTP) maintenance. ZIP is a novel and cell-permeable inhibitor for PKMξ and therefore it can block LTP.
CAT# | R0804 |
CAS | 863987-12-6 |
Synonyms/Alias | ZIP;FLJ36473;DAPK3, active, GST tagged human;PKC Zeta Pseudosubstrate Inhibitory peptide;Protein kinase Cζ pseudosubstrate, myristoyl trifluoroacetate salt;N-(1-Oxotetradecyl)-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginylglycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucine |
M.F/Formula | C90H154N30O17 |
M.W/Mr. | 1982.4 |
Sequence | SIYRRGARRWRKL(Modifications: N-terminal myristyl) |
Labeling Target | Protein kinase Mζ (PKMζ) |
Activity | Inhibitor |
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