* Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).
Linkers, we can also call spacers, which can be used to link two molecules of interest to us. They are always flexible or stretched molecule. Depending on the field of design and application, we can construct plugins in peptides and different molecules to construct molecular structures that can be used for research. Generally, we can insert a linker between the peptide and the following molecules:
Different lengths of linkers can bind to any site on the peptide, usually via an amide bond. One common hydrophobic spacer is aminocaproic acid (Ahx), a common hydrophilic spacer is polyethylene glycol (PEG), and there are many other options. In recent years, PEGylation has been widely used method for improving the stability and bioavailability of peptides in vivo. If you need, please visit Peptide PEGylation.
Creative Peptides can provide linkers as shown below, including but not limited to the following examples:
Inserting a linker between peptide and other molecules can help:
References
Creative Peptides has accumulated a huge library of peptide knowledge including frontier peptide articles, application of peptides, useful tools, and more!
MCL 0020 is a synthetic tripeptide with the structure of Ac-D-2Nal-Arg-2Nal-NH2 (2-Nal= 3-(2-naphthyl)-L-alanine ...
The peptide st-Ht31 P, A-kinase anchoring protein (AKAP) inhibitor, has the negative control for st-Ht31. In DRG ...
Caprooyl tetrapeptide-3, an anti-wrinkle peptide, a reaction product of caproic acid and tetrapeptide-3, compris ...
NoxA1ds is derived from a peptide whose structure is based on a short sequence of an essential Nox subunit. It b ...
JIP1, a member of the JIPs family, was first discovered to promote JNK activation by combining multiple componen ...