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APIs

Buserelin Acetate

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CAT#
10-101-07
Synonyms/Alias
(Des-Gly10,D-Ser(tBu)6,Pro-NHEt9)-LHRH; Bigonist; HOE-766; HOE766; HOE 766; Profact; Receptal; Suprecur; Suprefact; Tiloryth; Hoe-766 MP; Hoe766 MP
CAS No.
57982-77-1 (net)
Sequence
Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt acetate salt
M.W/Mr.
1239.43
Molecular Formula
C60H86N16O13
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Buserelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction.
Description
Buserelin is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Areas of Interest
Hormonal therapy
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