Corticotropin

Corticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis.

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CAT#10-101-167
CAS9002-60-2,12427-33-7
Synonyms/AliasAdrendcorticotrophic hormone;ACTH;ACTH (1-39);Acthar;Adrenocorticotrophin;Adrenocorticotropic hormone;Corticotrophin;H.P. acthar gel
M.F/FormulaC207H308N56O58S
M.W/Mr.4541.06582
SequenceSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
Labeling TargetAdrenocorticotropic hormone receptor
ApplicationCorticotropin is for use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
ActivityAgonist
Biological ActivityCorticotropin is a diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
Areas of InterestNeurological Disease
FunctionsMelanocortin receptor activity
DiseaseWest syndrome
Stevens-Johnson syndrome
Exacerbation of multiple sclerosis
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