Irofulven is a semisynthetic sesquiterpene derivative of illudin S, a natural toxin isolated from the fungus Omphalotus illudens. Irofulven is more active in vitro against tumor cells of epithelial origin and is more resistant to deactivation by p53 loss and MDR1 than other alkylating agents.
CAT# | MFP-048 |
Chemical Structure | |
CAS | 158440-71-2 |
Synonyms/Alias | MGI 114; HMAF; 6-Hydroxymethylacylfulvene |
Chemical Name | (5'R)-5'-hydroxy-1'-(hydroxymethyl)-2',5',7'-trimethylspiro[cyclopropane-1,6'-indene]-4'-one |
M.F/Formula | C15H18O3 |
M.W/Mr. | 246.3 |
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