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L-Ornithine α-Ketoglutarate Monohydrate

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CAT#
10-101-118
Synonyms/Alias
OKG; OAKG; L-Ornithine 2-oxoglutarate monohydrate
CAS No.
5144-42-3 (net)
Sequence
H-Orn-OH . α-ketoglutarate (2:1)
M.W/Mr.
278.26
Molecular Formula
C5H12N2O2 · 0.5 C5H6O5 · 0.5 H2O
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Ornithine α-ketoglutarate (OKG) is a drug used in liver therapy. It is the salt formed from ornithine and alpha-ketoglutaric acid. It is also used to improve nutritional health in elderly patients.
Description
L-Ornithine is a non-essential amino acid, metabolized to generate L-arginine, which is further incorporated into proteins. α-Ketoglutarate is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. Acting as a co-substrate, α-Ketoglutarate also plays important function in oxidation reactions involving molecular oxygen.
Areas of Interest
Dietary nutrition & Hyperammonaemia Hepatic encephalopathy
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