LXW7, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC50 of 0.68 μM. LXW7 increases the phosphorylation of VEGFR-2 and activation of ERK1/2.
CAT# | R1876 |
CAS | 1313004-77-1 |
M.F/Formula | C29H48N12O12S2 |
M.W/Mr. | 820.89 |
Sequence | One Letter Code: CGRGDDVC Three Letter Code: Cys-Gly-Arg-Gly-Asp-Asp-Val-Cys-NH2 (Disulfide bridge:Cys1-Cys8) |
Purity | >98 % |
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