Triptorelin Pamoate

Triptorelin pamoate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.

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CAT#	10-101-101
CAS	57773-63-4 (net), 124508-66-3 (pamoate salt)
Synonyms/Alias	5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycine amide, 4,4'-methylenebis(3-hydroxy-2-naphthoate) (salt); Decapeptyl; Diphereline; Gonapeptyl; Luteinizing hormone-releasing factor (swine), 6-D-tryptophan-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecarboxylate) (salt); Pamorelin; Trelstar; Trelstar depot; Trelstar LA; Triptorelin embonate; UNII-08AN7WA2G0
M.F/Formula	C64H82N18O13
M.W/Mr.	1744.96
Sequence	Pyr-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2
Labeling Target	Gonadotropin-releasing hormone (GNRH) Receptor
Application	Triptorelin pamoate is classified as a gonadotropin releasing hormone (GnRH) agonist. In adult men with advanced prostate cancer, triptorelin pamoate can be used to help lower testosterone levels, which can be beneficial in stopping or slowing the growth of abnormal prostate tissue.
Activity	Agonist
Biological Activity	Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts.
Areas of Interest	Cancer Research Pituitary & Hypothalamic Hormones Veterinary Medicine
Functions	Peptide binding
Disease	Advanced Prostatic Carcinoma
Target	Gonadotropin-releasing hormone (GnRH)

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-01	Tetracosactide Acetate	2933.5	C136H210N40O31S	Inquiry
10-101-31	Sincalide Ammonium Salt	1143.3	C49H62N10O16S3	Inquiry
10-101-32	Somatostatin Acetate	1637.88		Inquiry
10-101-41	Splenopentin Acetate	813.89	C35H59N9O13	Inquiry
10-101-63	Taltirelin	477.46	C17H23N7O5	Inquiry

CAT#	Product Name	M.W	Molecular Formula	Inquiry
10-101-20	Goserelin Acetate	1269.43	C59H84N18O14	Inquiry
10-101-59	Liraglutide	3751.2	C172H265N43O51	Inquiry
R1574	Octreotide	1019.24	C₄₉H₆₆N₁₀O₁₀S₂	Inquiry
10-101-139	Myrcludex B			Inquiry
10-101-285	Teduglutide	3752.08	C164H252N44O55S	Inquiry
R1847	Sermaglutide	4114	C187H291N45O59	Inquiry
R1961	Carbetocin	988.2	C45H69N11O12S	Inquiry

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Source#	Synthetic
Long-term Storage Conditions	−20°C
Organism	Human