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Special Antigen Peptides Services

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Special Antigen Peptides Services

Peptide antigen, namely, a peptide used to trigger animal's immune system to develop antibodies specific to that peptide. Nowadays, the use of synthetic peptide antigens as immunogens has markedly increased, and this technique is also widely applied for immune research such as tumor immunotherapy etc. With ten years experience in antigen peptides supply, Creative Peptides is experienced in the synthesis of complex antigen peptides, such as glycopeptides or hyperphosphorylation peptides. 

Design of peptide antigens

Although many peptide sequences are immunogenic, not all of them are identically effective in generating antibodies when act against the target protein. Effective antibody generation depends on several factors that need to be considered at the very first stage of peptides designing.

Special antigen peptides services

Mimicking specific parts of the target protein, peptide antigens can provide much flexibility for scientific research. However, most of synthetic peptides are composed of 10AA -25 AA, which are too short to generate a strong immune response without prior conjugation to a carrier protein such as Keyhole Limpet Hemocyanin(KLH), Ovalbumin(OVA) or Thyroglobulin(Tg). Creative peptides specialists can help with antigen design to maximize the chances that the peptide used as antigen can generate sufficient and effective antibody.

Example of our glycopeptides for generation antibody

In recently years, there is an increasing attention focused on the function of glycopeptides. As we know, extracellular secreted proteins are often glycosylated, especially the extracellular segments. Glycoproteins are also the most important integral membrane proteins, and play a role in cell–cell interactions. With the increasing demand of antigen peptides, Creative Peptides is endeavour to support customers with superior antigen peptides services. Please kindly check below form for the glycosylation sites of Apolipoprotein J to generate mAbs as an example of our antigen peptides service.

Coupling
Sequence
Biotinyl covalent coupling BSA covalent coupling
EDALN(GlcNAc)ETRES Biotinyl-EDALN(GlcNAc)ETRES BSA- EDALN(GlcNAc)ETRES
PGVCN(GlcNAc)ETMMA Biotinyl- PGVCN(GlcNAc)ETMMA BSA- PGVCN(GlcNAc)ETMMA
EEFLN(GlcNAc)QSSP Biotinyl- EEFLN(GlcNAc)QSSP BSA- EEFLN(GlcNAc)QSSP
REIRHN(GlcNAc)STGC Biotinyl- REIRHN(GlcNAc)STGC BSA- REIRHN(GlcNAc)STGC
CSTNN(GlcNAc)PSQAK Biotinyl- CSTNN(GlcNAc)PSQAK BSA- CSTNN(GlcNAc)PSQAK
WKMLN(GlcNAc)TSSLE Biotinyl- WKMLN(GlcNAc)TSSLE BSA- WKMLN(GlcNAc)TSSLE
SRLAN(GlcNAc)LTQGE Biotinyl- SRLAN(GlcNAc)LTQGE BSA- SRLAN(GlcNAc)LTQGE

Product of antigen peptides
Peptide Pools

  1. Antigens from Infectious Diseases
  2. Collections
  3. Tumor Associated Antigens
  4. Control Pools

Tumor Antigen-derived Peptides

Last but not least, Creative Peptides also provide remarkable one-step services from synthesis peptides to generation antibody. We are confident in applying our experience, industry and regulatory knowledge to design actual strategic packages pertinent to customers’ project.

If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.

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