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APIs

Calcitonin (salmon)

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CAT#
10-101-08
Synonyms/Alias
Salcatonin; Salmon Calcitonin; Thyrocalcitonin (salmon); Ciba 47175-BA; Ciba47175-BA; Calcitrin; Calcitonin(1-32); Calcitonin (1-32); Calcitonin1-32; Calcitonin 1-32; Cibacalcin; UNII-I0IO929019; EINECS 244-276-2
CAS No.
47931-85-1 (net)
Sequence
H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 acetate salt (Disulfide bond)
M.W/Mr.
3431.9
Molecular Formula
C145H240N44O48S2
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Calcitonin (salmon) stimulates the bone formation and inhibits the bone resorption in postmenopausal osteoporotic women.
Description
Calcitonin (salmon) is a 32-amino acid polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid, and in many other animals in the ultimobranchial body. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). The calcitonin receptor has been cloned and shown to be a member of the seven-transmembrane, G protein-coupled receptor family.
Areas of Interest
Diseases
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