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APIs

Histrelin Acetate

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CAT#
10-101-21
Synonyms/Alias
(Des-Gly10,D-His(Bzl)6,Pro-NHEt9)-LHRH
CAS No.
76712-82-8 (net)
Sequence
Pyr-His-Trp-Ser-Tyr-D-His(Bzl)-Leu-Arg-Pro-NHEt acetate salt
M.W/Mr.
1323.5
Molecular Formula
C66H86N18O12
Source
Synthetic
Long-term Storage Conditions
−20°C
Application
Histrelin is used to treat hormone-sensitive cancers of the prostate in men and uterine fibroids in women. In addition, histrelin has been proven to be highly effective in treating central precocious puberty in children.
Description
Histrelin acetate is a potent LHRH agonist. After a transient increase, continuous administration results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
Areas of Interest
Hormonal therapy
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